Antimicrobial resistance profile of samples isolated at a University Hospital in Amapá

Ana Karolina Pereira Gonçalves, Andressa Kelly Ferreira e Silva2 Flávia Mylla de Sousa Reis, Diogo Castanho Amaral, Maria Luisa Lima Barreto do Nascimento Aldo Aparecido Proietti Junior, Rubens Alex de Oliveira Menezes

Abstract

nfections Related to Health Care (IRAS) are acquired infections related to health care care and associated with antimicrobial-resistant microorganisms. Antimicrobial Resistance (AMR) is the inefficiency of antimicrobials against the growth and multiplication of microorganisms. The research sought to identify and reveal the microbial resistance profile of samples isolated from a Hospital Universitário da Região Norte da Amazonia Brasileira. This is an observational, cross-sectional study, of a descriptive nature and a quantitative approach, carried out by analyzing two collected data, two microbiological examinations of two non-HU hospitalized patients, during May 2023 to April 2024. For a total of 1,044 microbiological examinations of biological samples, two quais 68 (6.5%) showed bacterial growth. Gram-negative bacilli (GNB) were prevalent (66.2%), highlighting Pseudomonas aeruginosa (23.5%), Escherichia coli (19.1%) and Klebsiella pneumoniae (11.8%). Gram-positive cocci (CGP) (33.8%) were represented by coagulase-negative Staphylococcus (SCN) (23.5%) and Staphylococcus aureus (5.9%). The CGP are resistant to lincosamides (69.6%), aminoglycosides (65.2%), quinolones (65.2%), pencilins (60.9%) and macrolides (47.8%). The BGN show resistance to penicillins (77.8%), beta-lactamase inhibitors (68.9%), quinolones (66.7%), cephalosporins (57.8%) and aminoglycosides (55.6%). With the results it was possible to identify the main microorganisms responsible for hospital infections and to outline the non-HU antimicrobial resistance profile.

Published
2025-03-13