Prevalence of vulvovaginal candidiasis in Amazonas, Brazil

Adriana Sotero-Martins, Vivien M. J. D. Antony Van Roy, Hugo Valério Corrêa de Oliveira, Ormezinda C. Cristo Fernandes, Amanda Sotero Martins, Elvira Carvajal.

Abstract

Vulvovaginal candidiasis (VVC) is caused by abnormal growth of yeast on the female genital mucosa. We aimed to analyze the prevalence of VVC in Manaus, its association with pre-exposure factors and antifungal resistance. Study conducted in the public healthcare, involved 1226 women aged 13-84 years. The yeasts were isolated and identified using Candifast test. Symptomatic VVC patients were grouped in symptomatic with one episode in year (SVVC) and symptomatic with recurrent VVC (RVVC), had two or more episodes in year. The total vaginal yeast isolation occurred in 231 women (18.86%). Mixed resistance was observed in 39% of patients. The RVVC group (21.6%) had a higher percentage of positive test for Candida spp. than the symptomatic non-recurrent group (13%). The prevalence of non-albicans spp. demostrated the importance of identify the Candida spp. present in infected patients.

Author Biographies

Adriana Sotero-Martins, Fundação Oswaldo Cruz, Escola Nacional de Saúde Pública

Researcher of Oswaldo Cruz Foundation - ENSP

Vivien Marilyn Jean D´Amorim Antony Van Roy , Instituto Leônidas e Maria Deane, Fundação Oswaldo Cruz, Manaus, Amazonas, Brasil.

Senior Fellow of Oswaldo Cruz Foundation in the Amazon - ILMD

Hugo Valério Corrêa de Oliveira , Escola Superior de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Amazonas, Brasil.

Post-graduate student at the Federal University of Amazonas (UFAM), Associate Professor of State University of Amazonas (UEA)

Ormezinda Celeste Cristo Fernandes , Instituto Leônidas e Maria Deane, Fundação Oswaldo Cruz, Manaus, Amazonas, Brasil.

Researcher of Oswaldo Cruz Foundation - ILMD

Amanda Sotero Martins, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brasil.

Biology Student at the Rio de Janeiro State University - UERJ

Elvira Carvajal, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brasil.

Researcher and Professor at the Rio de Janeiro State University - UERJ

Published
2022-03-15