Diferenças entre os Desfechos de Tratamento da Tuberculose em Casos de Coinfecção TB-HIV no Amazonas

Abstract

Tuberculosis (TB) is a respiratory disease that can be treated and cured but still impacts millions. Co-infection with the human immunodeficiency virus (HIV) is a factor in disease progression, with TB being the main cause of mortality among people living with HIV. This study aimed to identify differences in TB treatment outcomes in cases of TB-HIV co-infection in the state of Amazonas. The research used an ecological study with data on new TB cases. The variables analyzed included treatment outcome (cure, abandonment, death, failure and drug-resistant TB) and aspects related to the patient, such as clinical and laboratory. TB incidence rates were similar between the groups (TB only or TB-HIV), however treatment outcomes showed significant differences for co-infected cases: low cure rate, high default rate, higher incidence in men aged 30 to 39 years, mixed clinical form and comorbidities. These differences indicate that coinfected patients require a different treatment approach. Furthermore, unfavorable outcomes in cases of TB-HIV co-infection demonstrate greater severity for patients and represent additional challenges for TB control programs.